sowpati lab logo
2025

Nuclear compression-mediated DNA damage drives ATR-dependent Lamin expression and mouse ESC differentiation

Roy T, Ghosh S, Piplani N, Sthanam LK, Tiwary N, Dhar S, Konyak WCW, Panigrahi SS, Singh P, Sowpati DT, Nair S, Kumar S, Shekar PC, Sen S.

Programmed cell revival from imminent cell death enhances tissue repair and regeneration

Dhar K, Jena KK, Mehto S, Sahu R, Murmu KC, Mahajan AA, Behera S, Putchala RK, Mathew RJ, Bal R, Kundu S, Das SK, Chauhan S, Satapathy S, Yadav R, Priyadarsini S, Padala KR, Namdigalla P, Mishra S, Muralidhara P, Bansal K, Sannula K, Prasad P, Bokara KK, Sowpati DT, Ghosh-Roy A, Mahapatra PK, Khadilkar RJ, Yelagandula R, Chauhan S.

Analysis of tandem repeats in seven telomere-to-telomere primate genomes

Sharma A, Sowpati DT.

Elucidating neural molecular mechanisms underlying metabolic disorders-induced neuropsychiatric disorders in mice on prolonged high fructose diet

Singh S, Singh NK, Srividya K, Bhat UA, Sowpati DT, Chakravarty S, Kumar A.

ATaRVa: Analysis of Tandem Repeat Variation from Long Read Sequencing data

Abishek Kumar Sivakumar, Sriram Sudarsanam, Anukrati Sharma, Akshay Kumar Avvaru, Divya Tej Sowpati

Mapping genetic diversity with the GenomeIndia project

Bhattacharyya C, Subramanian K, Uppili B, Biswas NK, Ramdas S, Tallapaka KB, Arvind P, Rupanagudi KV, Maitra A, Nagabandi T, De T, Singh K, Sharma P, Sharma N, Raghav SK, Prasad P, Soniya EV, Jaleel A, Nelson Sathi S, Joshi M, Joshi C, Lahiri M, Dixit S, Shashidhara LS, Senthil Kumar N, Lalhruaitluanga H, Nundanga L, Shivakumar V, Venkatasubramanian G, Rao NP, Ganie MA, Wani IA, Jha G, Dalal A, Bashyam MD, Varadwaj PK, Bs S, Simmhan Y, Jain C, Sundar D, Gupta I, Yadav P, Sinha H, Narayanan M, Raman K, Padinjat R, Sabarinathan R; GenomeIndia Consortium; Narahari Y, Ravindranath V, Thangaraj K, Sowpati DT, Faruq M, Basu A, Kahali B.

Endogamy and high prevalence of deleterious mutations in India: evidence from strong founder events

Machha P, Gopalan A, Elangovan Y, Veeravalli SCM, Sowpati DT, Thangaraj K.

Ribbit: Accurate identification and annotation of complex tandem repeat sequences in genomes

Akshay Kumar Avvaru, Anukrati Sharma, Divya Tej Sowpati

Enhanced resolution of optical genome mapping utilizing telomere-to-telomere reference in genetic disorders

Banu S, Mk K, George JK, Siby E, Bhagat R, Ms S, Patil SJ, Phadke SR, Sowpati DT, Tallapaka KB.
2024

Bathing-suit ichthyosis: A rare but valuable entity for developing personalised pathogenesis-based therapies for autosomal recessive congenital ichthyosis

Tandon S, Konda SC, Kola R, Sowpati DT, Tallapaka KB, Yenamandra VK.

Comprehensive benchmarking of tools for nanopore-based detection of DNA methylation

Onkar Kulkarni, Reuben Jacob Mathew, Lamuk Zaveri, Rhea Jana, Nitesh Kumar Singh, Sreenivas Ara, Karthik Bharadwaj Tallapaka, Divya Tej Sowpati

Divergent downstream biosynthetic pathways are supported by <sc>L</sc>-cysteine synthases of Mycobacterium tuberculosis

Khan MZ, Hunt DM, Singha B, Kapoor Y, Singh NK, Prasad DVS, Dharmarajan S, Sowpati DT, de Carvalho LPS, Nandicoori VK.

Modulation of Nuclear Receptor 4A1 Expression Improves Insulin Secretion in a Mouse Model of Chronic Pancreatitis

Sheethal G, Verma A, Mall R, Parsa KV, Tokala RK, Bynigeri R, Pondugala PK, Vemula K, Sai Latha S, Sowpati DT, Singh SS, Rao GV, Talukdar R, Kanneganti TD, Reddy DN, Sasikala M.

Antimicrobial resistance landscape in a metropolitan city context using open drain wastewater-based metagenomic analysis

Madhukar MK, Singh N, Iyer VR, Sowpati DT, Tallapaka KB, Mishra RK, Moharir SC.

NEMO: Improved and accurate models for identification of 6mA using Nanopore sequencing

Onkar Kulkarni, Lamuk Zaveri, Reuben Jacob Mathew, Nitesh Kumar Singh, Sreenivas Ara, Shambhavi Garde, Manjula Reddy, Karthik Bharadwaj Tallapaka, Divya Tej Sowpati
2023

Transcriptional changes during isoproterenol-induced cardiac fibrosis in mice

Nanda D, Pant P, Machha P, Sowpati DT, Kumarswamy R.

The heparin-binding hemagglutinin protein of Mycobacterium tuberculosis is a nucleoid-associated protein

Keshavam CC, Naz S, Gupta A, Sanyal P, Kochar M, Gangwal A, Sangwan N, Kumar N, Tyagi E, Goel S, Singh NK, Sowpati DT, Khare G, Ganguli M, Raze D, Locht C, Basu-Modak S, Gupta M, Nandicoori VK, Singh Y.

A cross-sectional study on the nasopharyngeal microbiota of individuals with SARS-CoV-2 infection across three COVID-19 waves in India

Bose T, Wasimuddin, Acharya V, Pinna NK, Kaur H, Ranjan M, SaiKrishna J, Nagabandi T, Varma B, Tallapaka KB, Sowpati DT, Haque MM, Dutta A, Siva AB, Mande SS.

The unique N-terminal region of Mycobacterium tuberculosis sigma factor A plays a dominant role in the essential function of this protein

Singha B, Behera D, Khan MZ, Singh NK, Sowpati DT, Gopal B, Nandicoori VK.
2022

Structural and developmental dynamics of Matrix associated regions in Drosophila melanogaster genome

Sureka R, Avvaru AK, Sowpati DT, Pathak RU, Mishra RK.

Clinical outcomes in individuals hospitalized with SARS-CoV-2 Delta variant (B.1.617.2) who had been vaccinated with Covishield (ChAdOx1) and Covaxin (BBV-152)

Munigela A, Sowpati DT, M S, Banu S, Siva AB, V JK, Nutalapati C, Vishnubhotla R, Kulkarni A, Mukherjee P, Zaveri L, Rao GV, Tallapaka KB, Nageshwar Reddy D; CCMB COVID-19 Team, AIG Hospitals COVID-19 Vaccine Study Team.

SARS-CoV-2 Variant Delta Potently Suppresses Innate Immune Response and Evades Interferon-Activated Antiviral Responses in Human Colon Epithelial Cells

Tandel D, Sah V, Singh NK, Potharaju PS, Gupta D, Shrivastava S, Sowpati DT, Harshan KH.

Transmission of B.1.617.2 Delta variant between vaccinated healthcare workers

Kemp SA, Cheng MTK, Hamilton WL, Kamelian K; Indian SARS-CoV-2 Genomics Consortium (INSACOG); Singh S, Rakshit P, Agrawal A, Illingworth CJR, Gupta RK.

SARS-CoV-2 seroprevalence in the city of Hyderabad, India in early 2021

Laxmaiah A, Rao NM, Arlappa N, Babu J, Kumar PU, Singh P, Sharma D, Anumalla VM, Kumar TS, Sabarinathan R, Kumar MS, Ananthan R, Basha DA, Blessy PPS, Kumar DC, Devaraj P, Devendra S, Kumar MM, Meshram II, Kumar BN, Sharma P, Raghavendra P, Raghu P, Rao KR, Ravindranadh P, Kumar BS, Sarika G, Rao JS, Surekha MV, Sylvia F, Kumar D, Rao GS, Tallapaka KB, Sowpati DT, Srivastava S, Murhekar VM, Hemalatha R, Mishra RK.

Spatio-temporal dynamics of intra-host variability in SARS-CoV-2 genomes

Pathak AK, Mishra GP, Uppili B, Walia S, Fatihi S, Abbas T, Banu S, Ghosh A, Kanampalliwar A, Jha A, Fatma S, Aggarwal S, Dhar MS, Marwal R, Radhakrishnan VS, Ponnusamy K, Kabra S, Rakshit P, Bhoyar RC, Jain A, Divakar MK, Imran M, Faruq M, Sowpati DT, Thukral L, Raghav SK, Mukerji M.

Effectiveness of REGEN-COV antibody cocktail against the B.1.617.2 (delta) variant of SARS-CoV-2: A cohort study

Kumar V J, Banu S, Sasikala M, Parsa KVL, Sowpati DT, Yadav R, Tallapaka KB, Siva AB, Vishnubhotla R, Rao GV, Reddy DN.
2021

Genomic characterization and epidemiology of an emerging SARS-CoV-2 variant in Delhi, India

Dhar MS, Marwal R, Vs R, Ponnusamy K, Jolly B, Bhoyar RC, Sardana V, Naushin S, Rophina M, Mellan TA, Mishra S, Whittaker C, Fatihi S, Datta M, Singh P, Sharma U, Ujjainiya R, Bhatheja N, Divakar MK, Singh MK, Imran M, Senthivel V, Maurya R, Jha N, Mehta P, A V, Sharma P, Vr A, Chaudhary U, Soni N, Thukral L, Flaxman S, Bhatt S, Pandey R, Dash D, Faruq M, Lall H, Gogia H, Madan P, Kulkarni S, Chauhan H, Sengupta S, Kabra S; Indian SARS-CoV-2 Genomics Consortium (INSACOG)‡; Gupta RK, Singh SK, Agrawal A, Rakshit P, Nandicoori V, Tallapaka KB, Sowpati DT, Thangaraj K, Bashyam MD, Dalal A, Sivasubbu S, Scaria V, Parida A, Raghav SK, Prasad P, Sarin A, Mayor S, Ramakrishnan U, Palakodeti D, Seshasayee ASN, Bhat M, Shouche Y, Pillai A, Dikid T, Das S, Maitra A, Chinnaswamy S, Biswas NK, Desai AS, Pattabiraman C, Manjunatha MV, Mani RS, Arunachal Udupi G, Abraham P, Atul PV, Cherian SS.

DiviSSR: Simple arithmetic for efficient identification of tandem repeats

Akshay Kumar Avvaru, Rakesh K Mishra, Divya Tej Sowpati

Host transcriptional response to SARS-CoV-2 infection in COVID-19 patients

Singh NK, Srivastava S, Zaveri L, Bingi TC, Mesipogu R, Kumar V S, Gaur N, Hajirnis N, Machha P, Shambhavi S, Khan S, Soujanya M, Nagabandi T, Mishra RK, Tallapaka KB, Sowpati DT.

Evidence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Reinfection Without Mutations in the Spike Protein

Kulkarni O, Narreddy S, Zaveri L, Kalal IG, Tallapaka KB, Sowpati DT.

SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion

Mlcochova P, Kemp SA, Dhar MS, Papa G, Meng B, Ferreira IATM, Datir R, Collier DA, Albecka A, Singh S, Pandey R, Brown J, Zhou J, Goonawardane N, Mishra S, Whittaker C, Mellan T, Marwal R, Datta M, Sengupta S, Ponnusamy K, Radhakrishnan VS, Abdullahi A, Charles O, Chattopadhyay P, Devi P, Caputo D, Peacock T, Wattal C, Goel N, Satwik A, Vaishya R, Agarwal M; Indian SARS-CoV-2 Genomics Consortium (INSACOG); Genotype to Phenotype Japan (G2P-Japan) Consortium; CITIID-NIHR BioResource COVID-19 Collaboration; Mavousian A, Lee JH, Bassi J, Silacci-Fegni C, Saliba C, Pinto D, Irie T, Yoshida I, Hamilton WL, Sato K, Bhatt S, Flaxman S, James LC, Corti D, Piccoli L, Barclay WS, Rakshit P, Agrawal A, Gupta RK.

SARS-CoV-2 genomics: An Indian perspective on sequencing viral variants

Srivastava S, Banu S, Singh P, Sowpati DT, Mishra RK.

C3G Regulates STAT3, ERK, Adhesion Signaling, and Is Essential for Differentiation of Embryonic Stem Cells

Vishnu VV, Muralikrishna B, Verma A, Nayak SC, Sowpati DT, Radha V, Shekar PC.

Drosophila Hox genes induce melanized pseudo-tumors when misexpressed in hemocytes

Titus Ponrathnam, Ravina Saini, Sofia Banu, Rakesh K Mishra

Tissue-specific transcriptome recovery on withdrawal from chronic alcohol exposure in zebrafish

Banu S, Srivastava S, Mohammed A, Kushawah G, Sowpati DT, Mishra RK.
2020

A Distinct Phylogenetic Cluster of Indian Severe Acute Respiratory Syndrome Coronavirus 2 Isolates

Banu S, Jolly B, Mukherjee P, Singh P, Khan S, Zaveri L, Shambhavi S, Gaur N, Reddy S, Kaveri K, Srinivasan S, Gopal DR, Siva AB, Thangaraj K, Tallapaka KB, Mishra RK, Scaria V, Sowpati DT.

Transcriptomic dataset of zebrafish tissues following chronic alcohol exposure and withdrawal

Banu S, Srivastava S, Mohammed A, Kushawah G, Sowpati DT, Mishra RK.

Interplay of pericentromeric genome organization and chromatin landscape regulates the expression of Drosophila melanogaster heterochromatic genes

Saha P, Sowpati DT, Soujanya M, Srivastava I, Mishra RK.

Long-Read Genome Sequencing and Assembly of Leptopilina boulardi: A Specialist Drosophila Parasitoid

Khan S, Sowpati DT, Srinivasan A, Soujanya M, Mishra RK.

Sperm methylome alterations following yoga-based lifestyle intervention in patients of primary male infertility: A pilot study

Shilpa Bisht, Sofia Banu, Surabhi Srivastava, Rashmi U. Pathak, Rajeev Kumar, Rima Dada, Rakesh K. Mishra

MSDB: a comprehensive, annotated database of microsatellites

Avvaru AK, Sharma D, Verma A, Mishra RK, Sowpati DT.
2019

Patterns of microsatellite distribution across eukaryotic genomes

Srivastava S, Avvaru AK, Sowpati DT, Mishra RK.

The putative Neuronatin imprint control region is an enhancer that also regulates the Blcap gene

Thamban T, Sowpati DT, Pai V, Nithianandam V, Abe T, Shioi G, Mishra RK, Khosla S.

Epigenomic and genomic landscape of Drosophila melanogaster heterochromatic genes

Saha P, Sowpati DT, Mishra RK.
2018

PERF: an exhaustive algorithm for ultra-fast and efficient identification of microsatellites from large DNA sequences

Avvaru AK, Sowpati DT, Mishra RK.
2017

C-State: an interactive web app for simultaneous multi-gene visualization and comparative epigenetic pattern search

Sowpati DT, Srivastava S, Dhawan J, Mishra RK.

MSDB: A Comprehensive Database of Simple Sequence Repeats

Avvaru AK, Saxena S, Sowpati DT, Mishra RK.
older

Single Amino Acid Repeats in the Proteome World: Structural, Functional, and Evolutionary Insights

Kumar AS, Sowpati DT, Mishra RK.

Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection

Sharma G, Sowpati DT, Singh P, Khan MZ, Ganji R, Upadhyay S, Banerjee S, Nandicoori VK, Khosla S.

A ChIP-on-chip tiling array approach detects functional histone-free regions associated with boundaries at vertebrate HOX genes

Srivastava S, Sowpati DT, Garapati HS, Puri D, Dhawan J, Mishra RK.

Expansion of the polycomb system and evolution of complexity

Sowpati DT, Ramamoorthy S, Mishra RK.

Human mesenchymal stem cells: New sojourn of bacterial pathogens

Kohli S, Singh Y, Sowpati DT, Ehtesham NZ, Dobrindt U, Hacker J, Hasnain SE.

Gene cooption in mycobacteria and search for virulence attributes: comparative proteomic analyses of Mycobacterium tuberculosis, Mycobacterium indicus pranii and other mycobacteria

Singh Y, Kohli S, Sowpati DT, Rahman SA, Tyagi AK, Hasnain SE.

An intronic DNA sequence within the mouse Neuronatin gene exhibits biochemical characteristics of an ICR and acts as a transcriptional activator in Drosophila

Sowpati DT, Thiagarajan D, Sharma S, Sultana H, John R, Surani A, Mishra RK, Khosla S.