Publications

Papers and preprints from the lab, spanning population and clinical genetics, epigenetics, method development, and microbial surveillance.

60 publications
2026

CHFR gene variations: A novel cause for hereditary cancer predisposition?

Comprehensive benchmarking of tools for nanopore-based detection of DNA methylation

Rapgef1 paralog-mediated regulation of Wnt/β-catenin signaling orchestrates early embryo tissue patterning and morphogenesis

Genomic insights into antimicrobial resistance in ocular pathogens from India

Metagenomic profiling of antimicrobial resistance in wastewater from metropolitan cities of India

An Atlas of Indian Genetic Diversity

Whole-Genome Landscape of Breast Cancers from India shows Distinct Clinically Actionable Subtypes

ATaRVa: Analysis of Tandem Repeat Variation from Long Read Sequencing data

NEMO: Improved and accurate models for identification of 6mA using Nanopore sequencing

2025

Analysis of tandem repeats in seven telomere-to-telomere primate genomes

Nuclear compression-mediated DNA damage drives ATR-dependent Lamin expression and mouse ESC differentiation

Programmed cell revival from imminent cell death enhances tissue repair and regeneration

Elucidating neural molecular mechanisms underlying metabolic disorders-induced neuropsychiatric disorders in mice on prolonged high fructose diet

Mapping genetic diversity with the GenomeIndia project

Endogamy and high prevalence of deleterious mutations in India: evidence from strong founder events

Enhanced resolution of optical genome mapping utilizing telomere-to-telomere reference in genetic disorders

Ribbit: Accurate identification and annotation of complex tandem repeat sequences in genomes

2024

Bathing-suit ichthyosis: A rare but valuable entity for developing personalised pathogenesis-based therapies for autosomal recessive congenital ichthyosis

Divergent downstream biosynthetic pathways are supported by <sc>L</sc>-cysteine synthases of Mycobacterium tuberculosis

Modulation of Nuclear Receptor 4A1 Expression Improves Insulin Secretion in a Mouse Model of Chronic Pancreatitis

Antimicrobial resistance landscape in a metropolitan city context using open drain wastewater-based metagenomic analysis

2023

Transcriptional changes during isoproterenol-induced cardiac fibrosis in mice

The heparin-binding hemagglutinin protein of Mycobacterium tuberculosis is a nucleoid-associated protein

A cross-sectional study on the nasopharyngeal microbiota of individuals with SARS-CoV-2 infection across three COVID-19 waves in India

The unique N-terminal region of Mycobacterium tuberculosis sigma factor A plays a dominant role in the essential function of this protein

De novo genome assembly and annotation of the saw-scaled viper Echis carinatus, a medically important venomous snake in the Indian Subcontinent

Efficient self-organization of blastoids solely from mouse ESCs is facilitated by transient reactivation of 2C gene network

2022

Structural and developmental dynamics of Matrix associated regions in Drosophila melanogaster genome

Clinical outcomes in individuals hospitalized with SARS-CoV-2 Delta variant (B.1.617.2) who had been vaccinated with Covishield (ChAdOx1) and Covaxin (BBV-152)

SARS-CoV-2 Variant Delta Potently Suppresses Innate Immune Response and Evades Interferon-Activated Antiviral Responses in Human Colon Epithelial Cells

Transmission of B.1.617.2 Delta variant between vaccinated healthcare workers

SARS-CoV-2 seroprevalence in the city of Hyderabad, India in early 2021

Spatio-temporal dynamics of intra-host variability in SARS-CoV-2 genomes

Effectiveness of REGEN-COV antibody cocktail against the B.1.617.2 (delta) variant of SARS-CoV-2: A cohort study

2021

Genomic characterization and epidemiology of an emerging SARS-CoV-2 variant in Delhi, India

Host transcriptional response to SARS-CoV-2 infection in COVID-19 patients

Evidence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Reinfection Without Mutations in the Spike Protein

SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion

SARS-CoV-2 genomics: An Indian perspective on sequencing viral variants

C3G Regulates STAT3, ERK, Adhesion Signaling, and Is Essential for Differentiation of Embryonic Stem Cells

Tissue-specific transcriptome recovery on withdrawal from chronic alcohol exposure in zebrafish

Genomic analysis of SARS-CoV-2 breakthrough infections from Varanasi, India

2020

A Distinct Phylogenetic Cluster of Indian Severe Acute Respiratory Syndrome Coronavirus 2 Isolates

Transcriptomic dataset of zebrafish tissues following chronic alcohol exposure and withdrawal

Interplay of pericentromeric genome organization and chromatin landscape regulates the expression of Drosophila melanogaster heterochromatic genes

Long-Read Genome Sequencing and Assembly of Leptopilina boulardi: A Specialist Drosophila Parasitoid

MSDB: a comprehensive, annotated database of microsatellites

Older

PERF: an exhaustive algorithm for ultra-fast and efficient identification of microsatellites from large DNA sequences

C-State: an interactive web app for simultaneous multi-gene visualization and comparative epigenetic pattern search

MSDB: A Comprehensive Database of Simple Sequence Repeats

Single Amino Acid Repeats in the Proteome World: Structural, Functional, and Evolutionary Insights

Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection

Expansion of the polycomb system and evolution of complexity

Human mesenchymal stem cells: New sojourn of bacterial pathogens

A ChIP-on-chip tiling array approach detects functional histone-free regions associated with boundaries at vertebrate HOX genes

Gene cooption in mycobacteria and search for virulence attributes: comparative proteomic analyses of Mycobacterium tuberculosis, Mycobacterium indicus pranii and other mycobacteria

An intronic DNA sequence within the mouse Neuronatin gene exhibits biochemical characteristics of an ICR and acts as a transcriptional activator in Drosophila