Sowpati Lab

Centre for Cellular & Molecular Biology · Hyderabad, India

Genomics · Epigenetics · Algorithms · Big Data

About Us

We study how genomic variation across Indian populations shapes health and disease — mapping structural variants and tandem repeats through large-scale sequencing, tracing epigenetic differences between cell types with single-cell genomics, and building the computational methods needed to analyze it all.

Meet the team →
Sowpati Lab group photo

Research Themes

01

Population Genomics

Mapping SNPs, structural variation, and short tandem repeats across healthy Indian populations to build a reference for disease context.

02

Epigenetics

Building accurate 6mA and 5mC detection models from long-read nanopore data to study cell-type-specific gene regulation.

03

Microbial Genetics

Wastewater-based metagenomic surveillance for pathogen load and antimicrobial resistance across India.

04

Algorithms and AI

Novel algorithms for rapid tandem-repeat identification at population scale, and ML models for long-read epigenomic analysis.

Lab News

Sep 2026

Dr Hardip Patel, ANU, visited the lab, discussed with the students, and delivered a talk on “Indigenous Australian genomics resources for precision medicine”.

Sep 2026

🎉 Onkar and Pooja presented posters at the Genomics India Conference 2026, Bengaluru.

Sep 2026

Tej presented the work on studying DNA methylation using nanopore sequencing at the GIC 2026, Bengaluru.

Aug 2026

Tej talks about ATaRVa at the Nanopore Tech Day at TTCRC, Kolkata.

Tools

Open-source tools built in the lab for tandem-repeat analysis, epigenomics, and genome exploration.

Recent Publications

Showing 8 of 60
2026

CHFR gene variations: A novel cause for hereditary cancer predisposition?

Comprehensive benchmarking of tools for nanopore-based detection of DNA methylation

Rapgef1 paralog-mediated regulation of Wnt/β-catenin signaling orchestrates early embryo tissue patterning and morphogenesis

Genomic insights into antimicrobial resistance in ocular pathogens from India

Metagenomic profiling of antimicrobial resistance in wastewater from metropolitan cities of India

An Atlas of Indian Genetic Diversity

Whole-Genome Landscape of Breast Cancers from India shows Distinct Clinically Actionable Subtypes

ATaRVa: Analysis of Tandem Repeat Variation from Long Read Sequencing data

Interested in joining us?

We're always looking for motivated graduate students, project associates, and post-docs interested in computational genomics. Write to us with your CV and a cover letter.

CSIR–CCMB, Hyderabad 500007

Room 509, East Wing, Fourth Floor

+91 040 2176 2862

CCMB campus